Antimalarial activity of WR 243251, a Dihydroacridinedione.

WR 243251 is a dihydroacridinedione that was evaluated for antimalarial blood schizonticidal activity in vitro and in vivo. The in vitro doses calculated to kill 50% of organisms were 11 nM for a chloroquine-susceptible, mefloquine-resistant standard strain and 25 nM for a chloroquine- and pyrimetha...

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Main Authors: Berman, J, Brown, L, Miller, R, Andersen, S L, McGreevy, P, Schuster, B G, Ellis, W, Ager, A, Rossan, R
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC284632/
https://ncbi.nlm.nih.gov/pubmed/7986005
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