Refined Geographic Distribution of the Oriental ALDH2*504Lys (nee 487Lys) Variant

Mitochondrial aldehyde dehydrogenase (ALDH2) is one of the most important enzymes in human alcohol metabolism. The oriental ALDH2*504Lys variant functions as a dominant negative greatly reducing activity in heterozygotes and abolishing activity in homozygotes. This allele is associated with serious...

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Main Authors: Li, Hui, Borinskaya, Svetlana, Yoshimura, Kimio, Kal’ina, Nina, Marusin, Andrey, Stepanov, Vadim A., Qin, Zhendong, Khaliq, Shagufta, Lee, Mi-Young, Yang, Yajun, Mohyuddin, Aisha, Gurwitz, David, Mehdi, Syed Qasim, Rogaev, Evgeny, Jin, Li, Yankovsky, Nikolay K., Kidd, Judith R., Kidd, Kenneth K.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846302/
https://ncbi.nlm.nih.gov/pubmed/19456322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2009.00517.x
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