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Molecular Similarity Methods for Predicting Cross-Reactivity With Therapeutic Drug Monitoring Immunoassays

Immunoassays are used for therapeutic drug monitoring (TDM) yet may suffer from cross-reacting compounds able to bind the assay antibodies in a manner similar to the target molecule. To our knowledge, there has been no investigation using computational tools to predict cross-reactivity with TDM immu...

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Detalhes bibliográficos
Main Authors: Krasowski, Matthew D., Siam, Mohamed G., Iyer, Manisha, Ekins, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846282/
https://ncbi.nlm.nih.gov/pubmed/19333148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e31819c1b83
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