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Cyclosporine Up-Regulates Krüppel-Like Factor-4 (KLF4) in Vascular Smooth Muscle Cells and Drives Phenotypic Modulation In Vivo

Cyclosporine A (CSA, calcineurin inhibitor) has been shown to block both vascular smooth muscle cell (VSMC) proliferation in cell culture and vessel neointimal formation following injury in vivo. The purpose of this study was to determine molecular and pathological effects of CSA on VSMCs. Using rea...

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Detaylı Bibliyografya
Asıl Yazarlar: Garvey, Sean M., Sinden, Daniel S., Schoppee Bortz, Pamela D., Wamhoff, Brian R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846029/
https://ncbi.nlm.nih.gov/pubmed/20089806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163949
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