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5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile.

5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83) is a selective anti-human immunodeficiency virus (HIV) agent. When tested in phytohemagglutinin-stimulated normal human peripheral blood lymphocytes against fresh clinical isolates of HIV type 1 (HIV-1) obtained from patients naive to AZT (3'-azido-3'...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Daluge, S M, Purifoy, D J, Savina, P M, St Clair, M H, Parry, N R, Dev, I K, Novak, P, Ayers, K M, Reardon, J E, Roberts, G B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7526782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.7.1590
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