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Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction

σ-1 receptors (Sig-1Rs) that bind diverse synthetic and endogenous compounds have been implicated in the pathophysiology of several human diseases such as drug addiction, depression, neurodegenerative disorders, pain-related disorders, and cancer. Sig-1Rs were identified recently as novel ligand-ope...

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Autori principali: Hayashi, Teruo, Fujimoto, Michiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845942/
https://ncbi.nlm.nih.gov/pubmed/20053954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.062539
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