Mouse-human immunoglobulin G1 chimeric antibodies with activities against Cryptococcus neoformans.

Passive antibody administration is a potentially useful approach for the therapy of human Cryptococcus neoformans infections. To evaluate the efficacy of the human immunoglobulin G1 (IgG1) constant region against C. neoformans and to construct murine antibody derivatives with reduced immunogenicitie...

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Hauptverfasser: Zebedee, S L, Koduri, R K, Mukherjee, J, Mukherjee, S, Lee, S, Sauer, D F, Scharff, M D, Casadevall, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC284584/
https://ncbi.nlm.nih.gov/pubmed/7979280
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