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Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

Chemical nociception, the detection of tissue-damaging chemicals, is important for animal survival and causes human pain and inflammation, but its evolutionary origins are largely unknown. Reactive electrophiles are a class of noxious compounds humans find pungent and irritating, like allyl isothioc...

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Detalhes bibliográficos
Main Authors: Kang, Kyeongjin, Pulver, Stefan R., Panzano, Vincent C., Chang, Elaine C., Griffith, Leslie C., Theobald, Douglas L., Garrity, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845738/
https://ncbi.nlm.nih.gov/pubmed/20237474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08848
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