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Clinical Protection from Falciparum Malaria Correlates with Neutrophil Respiratory Bursts Induced by Merozoites Opsonized with Human Serum Antibodies

BACKGROUND: Effective vaccines to combat malaria are urgently needed, but have proved elusive in the absence of validated correlates of natural immunity. Repeated blood stage infections induce antibodies considered to be the main arbiters of protection from pathology, but their essential functions h...

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Detalhes bibliográficos
Main Authors: Joos, Charlotte, Marrama, Laurence, Polson, Hannah E. J., Corre, Sandra, Diatta, Antoine-Marie, Diouf, Babacar, Trape, Jean-François, Tall, Adama, Longacre, Shirley, Perraut, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845614/
https://ncbi.nlm.nih.gov/pubmed/20360847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009871
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