Influence of stereochemistry on antiviral activities and resistance profiles of dideoxycytidine nucleosides.

beta-L-2',3'-Dideoxycytidine (beta-L-ddC) and beta-L-5-fluoro-2',3'-dideoxycytidine (5-F-beta-L-ddC) were prepared and shown to have potent activity against human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV). These compounds were compared with beta-D-2',3'-dideoxycytidine (beta-...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Van Draanen, N A, Tisdale, M, Parry, N R, Jansen, R, Dornsife, R E, Tuttle, J V, Averett, D R, Koszalka, G W
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1994
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.868
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