Influence of stereochemistry on antiviral activities and resistance profiles of dideoxycytidine nucleosides.

beta-L-2',3'-Dideoxycytidine (beta-L-ddC) and beta-L-5-fluoro-2',3'-dideoxycytidine (5-F-beta-L-ddC) were prepared and shown to have potent activity against human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV). These compounds were compared with beta-D-2',...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Van Draanen, N A, Tisdale, M, Parry, N R, Jansen, R, Dornsife, R E, Tuttle, J V, Averett, D R, Koszalka, G W
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518218/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.868
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