Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidine.

Mutants of feline immunodeficiency virus (FIV) were selected in cell culture in the continuous presence of 10 microM (each) 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxyinosine (ddI). These mutants (AIR-1 and AIR-3) displayed a 13-fold resistance to AZT but had less than a 2...

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Sparad:
Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Gobert, J M, Remington, K M, Zhu, Y Q, North, T W
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8031060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.861
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