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Association between a Literature-Based Genetic Risk Score and Cardiovascular Events in 19,313 Women

CONTEXT: While multiple genetic markers associated with cardiovascular disease (CVD) have been identified by genome wide association studies, their aggregate effect on risk beyond traditional factors is uncertain, particularly among women. OBJECTIVE: To test the predictive ability of a literature-ba...

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Bibliographic Details
Main Authors: Paynter, Nina P., Chasman, Daniel I., Pare, Guillaumé, Buring, Julie E., Cook, Nancy R., Miletich, Joseph P., Ridker, Paul M
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845522/
https://ncbi.nlm.nih.gov/pubmed/20159871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2010.119
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