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The Tetrahymena Argonaute-binding protein Giw1p directs a mature Argonaute-siRNA complex to the nucleus

Emerging evidence suggests that RNAi-related processes act both in the cytoplasm and in the nucleus. However, the process by which the RNAi machinery is transported into the nucleus remains poorly understood. The Tetrahymena Argonaute protein Twi1p localizes to the nucleus and is crucial for small R...

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Detalhes bibliográficos
Main Authors: Noto, Tomoko, Kurth, Henriette M., Kataoka, Kensuke, Aronica, Lucia, DeSouza, Leroi V., Siu, K.W. Michael, Pearlman, Ronald E., Gorovsky, Martin A., Mochizuki, Kazufumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845462/
https://ncbi.nlm.nih.gov/pubmed/20211138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.010
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