The cardiomyocyte lineage is critical for optimization of stem cell therapy in a mouse model of myocardial infarction

We recently described a murine embryonic stem cell (ESC) line engineered to express the activated Notch 4 receptor in a tetracycline (doxcycline; Dox) regulated fashion (tet-notch4 ESCs). Notch 4 induction in Flk1(+) hematopoietic and vascular progenitors from this line respecified them to a cardiov...

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Hauptverfasser: Adler, Eric D., Chen, Vincent C., Bystrup, Anne, Kaplan, Aaron D., Giovannone, Steven, Briley-Saebo, Karen, Young, Wilson, Kattman, Steve, Mani, Venkatesh, Laflamme, Michael, Zhu, Wei-Zhong, Fayad, Zahi, Keller, Gordon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Federation of American Societies for Experimental Biology 2010
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845427/
https://ncbi.nlm.nih.gov/pubmed/19940262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-135426
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