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The Beta-Binomial Distribution for Estimating the Number of False Rejections in Microarray Gene Expression Studies

In differential expression analysis of microarray data, it is common to assume independence among null hypotheses (and thus gene expression levels). The independence assumption implies that the number of false rejections V follows a binomial distribution and leads to an estimator of the empirical fa...

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Autors principals: Hunt, Daniel L., Cheng, Cheng, Pounds, Stanley
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845402/
https://ncbi.nlm.nih.gov/pubmed/20352014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2008.01.013
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