Pharmacokinetics of sparfloxacin in patients with renal impairment.

The pharmacokinetics of sparfloxacin were studied in 14 renal failure patients (group I, 7 with creatinine clearance of > 10 to 30 ml/min; and group II, 7 with creatinine clearance of < or = 10 ml/min) after a single oral dose of 400 mg. Plasma and urine samples were collected up to 144 h postdosing...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Fillastre, J P, Montay, G, Bruno, R, Etienne, I, Dhib, M, Vivier, N, Le Roux, Y, Guimart, C, Gay, G, Schott, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284534/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8031038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.733
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