Histamine N-methyltransferase Thr105Ile is not associated with Parkinson’s disease or essential tremor

A functional variant in the Histamine N-Methyltransferase gene (HNMT – rs11558538) resulting in a threonine to isoleucine substitution (Thr105Ile), has been shown to impair histamine degradation. Two recent studies reported that the threonine allele of this polymorphism might be a risk factor for Pa...

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Bibliografiske detaljer
Main Authors: Keeling, Brett H., Vilariño-Güell, Carles, Soto-Ortolaza, Alexandra I., Ross, Owen A., Uitti, Ryan J., Rajput, Alex, Wszolek, Zbigniew K., Farrer, Matthew J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845175/
https://ncbi.nlm.nih.gov/pubmed/19773194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2009.08.011
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