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Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity

BACKGROUND: The Tousled Like Kinases (TLKs) are involved in chromatin dynamics, including DNA replication and repair, transcription, and chromosome segregation. Indeed, the first two TLK1 substrates were identified as the histone H3 and Asf1 (a histone H3/H4 chaperone), which immediately suggested a...

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Detalhes bibliográficos
Autor principal: De Benedetti, Arrigo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845150/
https://ncbi.nlm.nih.gov/pubmed/20222959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-68
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