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Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes

Centromeric DNA forms two structures on the mitotic chromosome: the kinetochore, which interacts with kinetochore microtubules, and the inner centromere, which connects sister kinetochores. The assembly of the inner centromere is poorly understood. In this study, we show that the human Mis14 (hMis14...

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Bibliographische Detailangaben
Hauptverfasser: Kiyomitsu, Tomomi, Iwasaki, Osamu, Obuse, Chikashi, Yanagida, Mitsuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845078/
https://ncbi.nlm.nih.gov/pubmed/20231385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908096
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