Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B.

The therapeutic efficacy of the immunoglobulin G1 (IgG1) monoclonal antibody (MAb) 2H1 to the Cryptococcus neoformans capsular polysaccharide was studied with and without amphotericin B (AmB) in a murine model of intravenous (i.v.) infection. MAb and AmB were administered by intraperitoneal (i.p.) i...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Mukherjee, J, Zuckier, L S, Scharff, M D, Casadevall, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8203858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.3.580
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