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Nuclear factor-kappa B pathway and response in a phase II trial of bortezomib and docetaxel in patients with recurrent and/or metastatic head and neck squamous cell carcinoma

Background: Our previous study has shown that nuclear factor-kappa B (NF-κB)-signaling pathway was associated with a higher rate of recurrence in head and neck squamous cell carcinoma (HNSCC). The combination of bortezomib, an NF-κB inhibitor by inhibition of proteasomes, plus docetaxel was assessed...

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Detalhes bibliográficos
Main Authors: Chung, C. H., Aulino, J., Muldowney, N. J., Hatakeyama, H., Baumann, J., Burkey, B., Netterville, J., Sinard, R., Yarbrough, W. G., Cmelak, A. J., Slebos, R. J., Shyr, Y., Parker, J., Gilbert, J., Murphy, B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844946/
https://ncbi.nlm.nih.gov/pubmed/19850643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdp390
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