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Geometric Constraints for Porphyrin Binding in Helical Protein Binding Sites

Helical bundles which bind heme and porphyrin cofactors have been popular targets for cofactor-containing de novo protein design. By analyzing a highly non-redundant subset of the protein databank, we have determined a rotamer distribution for helical histidines bound to heme cofactors. Analysis of...

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Detalhes bibliográficos
Main Authors: Negron, Christopher, Fufezan, Christian, Koder, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844854/
https://ncbi.nlm.nih.gov/pubmed/18636480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22143
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