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Geometric Constraints for Porphyrin Binding in Helical Protein Binding Sites
Helical bundles which bind heme and porphyrin cofactors have been popular targets for cofactor-containing de novo protein design. By analyzing a highly non-redundant subset of the protein databank, we have determined a rotamer distribution for helical histidines bound to heme cofactors. Analysis of...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844854/ https://ncbi.nlm.nih.gov/pubmed/18636480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22143 |
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