Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice

OBJECTIVE: Accumulating evidence suggests that cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into epoxyeicosatrienoic acids (EETs), which play crucial and diverse roles in cardiovascular homeostasis. The anti-inflammatory, antihypertensive, and pro-proliferative effects of EETs sugg...

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Autors principals: Xu, Xizhen, Zhao, Chun Xia, Wang, Luyun, Tu, Ling, Fang, Xiaosai, Zheng, Changlong, Edin, Matthew L., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844847/
https://ncbi.nlm.nih.gov/pubmed/20068141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1241
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