C-C Chemokine Receptor 2 (CCR2) Regulates the Hepatic Recruitment of Myeloid Cells That Promote Obesity-Induced Hepatic Steatosis

OBJECTIVE: Obesity induces a program of systemic inflammation that is implicated in the development of many of its clinical sequelae. Hepatic inflammation is a feature of obesity-induced liver disease, and our previous studies demonstrated reduced hepatic steatosis in obese mice deficient in the C-C...

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Main Authors: Obstfeld, Amrom E., Sugaru, Eiji, Thearle, Marie, Francisco, Anne-Marie, Gayet, Constance, Ginsberg, Henry N., Ables, Eleanore V., Ferrante, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844839/
https://ncbi.nlm.nih.gov/pubmed/20103702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1403
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