Impact of rs361072 in the Phosphoinositide 3-Kinase p110β Gene on Whole-Body Glucose Metabolism and Subunit Protein Expression in Skeletal Muscle

OBJECTIVE: Phosphoinositide 3-kinase (PI3K) is a major effector in insulin signaling. rs361072, located in the promoter of the gene (PIK3CB) for the p110β subunit, has previously been found to be associated with homeostasis model assessment for insulin resistance (HOMA-IR) in obese subjects. The aim...

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Bibliografische gegevens
Hoofdauteurs: Ribel-Madsen, Rasmus, Poulsen, Pernille, Holmkvist, Johan, Mortensen, Brynjulf, Grarup, Niels, Friedrichsen, Martin, Jørgensen, Torben, Lauritzen, Torsten, Wojtaszewski, Jørgen F.P., Pedersen, Oluf, Hansen, Torben, Vaag, Allan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2010
Onderwerpen:
Brief Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844820/
https://ncbi.nlm.nih.gov/pubmed/20107106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1359
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