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Structural Determinants of Substrate Recognition in the HAD Superfamily Member D-Glycero-D-manno-Heptose 1,7-bisphosphate Phosphatase, GmhB

The Haloalkanoic Acid Dehalogenase (HAD) enzyme superfamily is the largest family of phosphohydrolases. In HAD members, the structural elements that provide the binding interactions that support substrate specificity are separated from those that orchestrate catalysis. For most HAD phosphatases a ca...

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Bibliographic Details
Main Authors: Nguyen, Henry, Wang, Liangbing, Huang, Hua, Peisach, Ezra, Dunaway-Mariano, Debra, Allen, Karen N.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844806/
https://ncbi.nlm.nih.gov/pubmed/20050614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902019q
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