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Multiple-dose pharmacokinetics of sparfloxacin and its influence on fecal flora.

In a randomized, double-blind, placebo-controlled, multiple-dose pharmacokinetic study, the safety and effect on intestinal flora of sparfloxacin (SPX) were determined in 12 healthy male volunteers (8 received SPX and 4 received a placebo). Following fasting and oral administration of 400 mg on day...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Ritz, M, Lode, H, Fassbender, M, Borner, K, Koeppe, P, Nord, C E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8203837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.3.455
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