LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

Deletion of 11q23–q24 is frequent in a diverse variety of malignancies, including breast and colorectal carcinoma, implicating the presence of a tumor suppressor gene at that chromosomal region. We examined a 6-Mb region on 11q23 by high-resolution deletion mapping, using both loss of heterozygosity...

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Bibliografiske detaljer
Main Authors: Ong, DCT, Ho, YM, Rudduck, C, Chin, K, Kuo, W-L, Lie, DKH, Chua, CLM, Tan, PH, Eu, KW, Seow-Choen, F, Wong, CY, Hong, GS, Gray, JW, Lee, ASG
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844776/
https://ncbi.nlm.nih.gov/pubmed/19734946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.266
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