The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames

Upstream open reading frames (uORFs) are protein coding elements in the 5′ leader of messenger RNAs. uORFs generally inhibit translation of the main ORF because ribosomes that perform translation elongation suffer either permanent or conditional loss of reinitiation competence. After conditional los...

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Hlavní autoři: Roy, Bijoyita, Vaughn, Justin N., Kim, Byung-Hoon, Zhou, Fujun, Gilchrist, Michael A., Von Arnim, Albrecht G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844622/
https://ncbi.nlm.nih.gov/pubmed/20179149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2056010
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