The h subunit of eIF3 promotes reinitiation competence during translation of mRNAs harboring upstream open reading frames

Upstream open reading frames (uORFs) are protein coding elements in the 5′ leader of messenger RNAs. uORFs generally inhibit translation of the main ORF because ribosomes that perform translation elongation suffer either permanent or conditional loss of reinitiation competence. After conditional los...

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Main Authors: Roy, Bijoyita, Vaughn, Justin N., Kim, Byung-Hoon, Zhou, Fujun, Gilchrist, Michael A., Von Arnim, Albrecht G.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844622/
https://ncbi.nlm.nih.gov/pubmed/20179149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2056010
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