TLR9 Polymorphisms Are Associated with Altered IFN-γ Levels in Children with Cerebral Malaria

Toll-like receptor (TLR) polymorphisms have been associated with disease severity in malaria infection, but mechanisms for this association have not been characterized. The TLR2, 4, and 9 single nucleotide polymorphism (SNP) frequencies and serum interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF...

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Hlavní autoři: Sam-Agudu, Nadia A., Greene, Jennifer A., Opoka, Robert O., Kazura, James W., Boivin, Michael J., Zimmerman, Peter A., Riedesel, Melissa A., Bergemann, Tracy L., Schimmenti, Lisa A., John, Chandy C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Tropical Medicine and Hygiene 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844552/
https://ncbi.nlm.nih.gov/pubmed/20348497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2010.09-0467
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