Intranasal Delivery of Influenza Subunit Vaccine Formulated with GEM Particles as an Adjuvant

Nasal administration of influenza vaccine has the potential to facilitate influenza control and prevention. However, when administered intranasally (i.n.), commercially available inactivated vaccines only generate systemic and mucosal immune responses if strong adjuvants are used, which are often as...

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Hlavní autoři: Saluja, Vinay, Amorij, Jean P., van Roosmalen, Maarten L., Leenhouts, Kees, Huckriede, Anke, Hinrichs, Wouter L. J., Frijlink, Henderik W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844513/
https://ncbi.nlm.nih.gov/pubmed/20058113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9168-2
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