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Hybrid Vigor and Transgenerational Epigenetic Effects on Early Mouse Embryo Phenotype

Mouse embryos display a strain-dependent propensity for blastomere cytofragmentation at the two-cell stage. The maternal pronucleus exerts a predominant, transcription-dependent effect on this phenotype, with lesser effects of the ooplasm and the paternal pronucleus. A parental origin effect has bee...

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Autori principali: Han, Zhiming, Mtango, Namdori R., Patel, Bela G., Sapienza, Carmen, Latham, Keith E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for the Study of Reproduction, Inc. 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844494/
https://ncbi.nlm.nih.gov/pubmed/18562704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.069096
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