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Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group.

Human immunodeficiency virus type 1 (HIV-1) isolates resistant to zidovudine (ZDV) have previously been demonstrated to exhibit in vitro cross-resistance to other similar dideoxynucleoside agents which contain a 3'-azido group. However, cross-resistance to didanosine (ddI) or dideoxycytidine (ddC) h...

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Sparad:
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Mayers, D L, Japour, A J, Arduino, J M, Hammer, S M, Reichman, R, Wagner, K F, Chung, R, Lane, J, Crumpacker, C S, McLeod, G X
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8192457/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.2.307
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