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Cytofluorometric analysis of chondrotoxicity of fluoroquinolone antimicrobial agents.

To better understand quinolone-related arthropathy, we conceived an experimental ex vivo model using cell cultures of articular chondrocytes issued from pretreated New Zealand White rabbits (NZW). Juvenile (4- to 5-week-old) NZW were orally dosed with ofloxacin or pefloxacin (300 mg/kg of body weigh...

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Autors principals: Hayem, G, Petit, P X, Levacher, M, Gaudin, C, Kahn, M F, Pocidalo, J J
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC284434/
https://ncbi.nlm.nih.gov/pubmed/8192451
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