NFκB Promotes Inflammation, Coagulation, and Fibrosis in the Aging Glomerulus

The peak prevalence of ESRD from glomerulosclerosis occurs at 70 to 79 years. To understand why old glomeruli are prone to failure, we analyzed the Fischer 344 rat model of aging under ad libitum-fed (rapid aging) and calorie-restricted (slowed aging) conditions. All glomerular cells contained genes...

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Detalhes bibliográficos
Main Authors: Wiggins, Jocelyn E., Patel, Sanjeevkumar R., Shedden, Kerby A., Goyal, Meera, Wharram, Bryan L., Martini, Sebastian, Kretzler, Matthias, Wiggins, Roger C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844310/
https://ncbi.nlm.nih.gov/pubmed/20150534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009060663
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