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Targeted Inactivation of EGF Receptor Inhibits Renal Collecting Duct Development and Function
The ureteric bud (UB) expresses high levels of the EGF receptor (EGFR) during kidney development, but its function in this setting is unclear. Here, Egfr mRNA was abundant in medullary portions of the UB trunk but absent from the branching UB tips during embryogenesis. Homozygous Egfr knockout did n...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844304/ https://ncbi.nlm.nih.gov/pubmed/20133479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070719 |
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