RANKL-mediated Reactive Oxygen Species Pathway That Induces Long Lasting Ca(2+) Oscillations Essential for Osteoclastogenesis

RANKL (receptor activator of NF-κB ligand) induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca(2+) ([Ca(2+)](i)). The [Ca(2+)](i) oscillations activate...

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Detalhes bibliográficos
Main Authors: Kim, Min Seuk, Yang, Yu-Mi, Son, Aran, Tian, Yu Shun, Lee, Syng-Ill, Kang, Sang Won, Muallem, Shmuel, Shin, Dong Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844141/
https://ncbi.nlm.nih.gov/pubmed/20048168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.051557
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