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Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the Ovarian Cancer Association Consortium

Fibroblast growth factor (FGF)-2 (basic) is a potent angiogenic molecule involved in tumour progression, and is one of several growth factors with a central role in ovarian carcinogenesis. We hypothesised that common single nucleotide polymorphisms (SNPs) in the FGF2 gene may alter angiogenic potent...

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Detalhes bibliográficos
Main Authors: Johnatty, Sharon E., Beesley, Jonathan, Chen, Xiaoqing, Spurdle, Amanda B., deFazio, Anna, Webb, Penelope M, Goode, Ellen L., Rider, David N., Vierkant, Robert A., Anderson, Stephanie, Wu, Anna H., Pike, Malcolm, Van Den Berg, David, Moysich, Kirsten, Ness, Roberta, Doherty, Jennifer, Rossing, Mary-Anne, Pearce, Celeste Leigh, Chenevix-Trench, Georgia
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844121/
https://ncbi.nlm.nih.gov/pubmed/19456219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1375/twin.12.3.269
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