Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases – the UK experience

BACKGROUND: The global lapatinib expanded access programme provided access to lapatinib combined with capecitabine for women with HER2-positive metastatic breast cancer (MBC) who previously received anthracycline, taxane and trastuzumab. METHODS: Progression-free survival (PFS) and safety data for 3...

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Autori principali: Sutherland, S, Ashley, S, Miles, D, Chan, S, Wardley, A, Davidson, N, Bhatti, R, Shehata, M, Nouras, H, Camburn, T, Johnston, S R D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844035/
https://ncbi.nlm.nih.gov/pubmed/20179708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605586
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