Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance.

A clinical isolate of Serratia marcescens (TN9106) produced a metallo beta-lactamase (IMP-1) which conferred resistance to imipenem and broad-spectrum beta-lactams. The blaIMP gene providing imipenem resistance was cloned and expressed in Escherichia coli HB101. The IMP-1 was purified from E. coli H...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Osano, E, Arakawa, Y, Wacharotayankun, R, Ohta, M, Horii, T, Ito, H, Yoshimura, F, Kato, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8141584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.1.71
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