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Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 µm size X-ray synchrotron beam

Crystallization of human membrane proteins in lipidic cubic phase often results in very small but highly ordered crystals. Advent of the sub-10 µm minibeam at the APS GM/CA CAT has enabled the collection of high quality diffraction data from such microcrystals. Herein we describe the challenges and...

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Bibliografske podrobnosti
Main Authors: Cherezov, Vadim, Hanson, Michael A., Griffith, Mark T., Hilgart, Mark C., Sanishvili, Ruslan, Nagarajan, Venugopalan, Stepanov, Sergey, Fischetti, Robert F., Kuhn, Peter, Stevens, Raymond C.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2009
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843980/
https://ncbi.nlm.nih.gov/pubmed/19535414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2009.0142.focus
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