Paclitaxel Combined with Inhibitors of Glucose and Hydroperoxide Metabolism Enhances Breast Cancer Cell Killing Via H(2)O(2)-Mediated Oxidative Stress

Cancer cells (relative to normal cells) demonstrate alterations in oxidative metabolism characterized by increased steady-state levels of reactive oxygen species [i.e. hydrogen peroxide, H(2)O(2)] that may be compensated for by increased glucose metabolism but the therapeutic significance of these o...

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Bibliographische Detailangaben
Hauptverfasser: Hadzic, Tanja, Aykin-Burns, Nükhet, Zhu, Yueming, Coleman, Mitchell C., Leick, Katie, Jacobson, Geraldine M., Spitz, Douglas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843822/
https://ncbi.nlm.nih.gov/pubmed/20083194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.01.018
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