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Ca(2+)/calmodulin-binding peptides block phototransduction in Limulus ventral photoreceptors: Evidence for direct inhibition of phospholipase C

Phototransduction in Limulus photoreceptors involves a G protein-mediated activation of phospholipase C (PLC) and subsequent steps involving InsP(3)-mediated release of intracellular Ca(2+). While exploring the role of calmodulin in this cascade, we found that intracellular injection of Ca(2+)/calmo...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Richard, Edwin A., Ghosh, Smita, Lowenstein, John M., Lisman, John E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.14095
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