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Timing of captopril administration determines radiation protection or radiation sensitization in a murine model of total body irradiation

OBJECTIVE: Angiotensin II (Ang II), a potent vasoconstrictor, affects the growth and development of hematopoietic cells. Mixed findings have been reported for the effects of ACE inhibitors on radiation-induced injury to the hematopoietic system. We investigated the consequences of different regimens...

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Main Authors: Davis, Thomas A., Landauer, Michael R., Mog, Steven R., Barshishat-Kupper, Michal, Zins, Stephen R., Amare, Mihret F., Day, Regina M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843794/
https://ncbi.nlm.nih.gov/pubmed/20116413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.01.004
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