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Duration of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity.

It is known that daily polyaspartic acid (PAA) protects the kidney from gentamicin nephrotoxicity in a standardized rat model despite marked cortical accumulation of the aminoglycoside. The present experiments address the duration of PAA protection. When administered every other day, PAA provided fu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Swan, S K, Gilbert, D N, Kohlhepp, S J, Leggett, J E, Kohnen, P W, Bennett, W M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1489205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2556
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