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Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Gαq

Mice lacking the α-subunit of the heterotrimeric guanine nucleotide binding protein G(q) (Gα(q)) are viable but suffer from ataxia with typical signs of motor discoordination. The anatomy of the cerebellum is not overtly disturbed, and excitatory synaptic transmission from parallel fibers to cerebel...

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Bibliografski detalji
Glavni autori: Offermanns, Stefan, Hashimoto, Kouichi, Watanabe, Masahiko, Sun, William, Kurihara, Hideo, Thompson, Richard F., Inoue, Yoshiro, Kano, Masanobu, Simon, Melvin I.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC28437/
https://ncbi.nlm.nih.gov/pubmed/9391157
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