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Activated CD4(+ )T cells enhance radiation effect through the cooperation of interferon-γ and TNF-α

BACKGROUND: Approaches that enhance radiation effect may lead to improved clinical outcome and decrease toxicity. Here we investigated whether activated CD4+ T cells (aCD4) can serve as an effective radiosensitizer. METHODS: CD4+ T cells were activated with anti-CD3 and anti-CD28 mAbs. Hela cells we...

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Autori principali: Wang, Yixiang, Radfar, Soroosh, Khong, Hung T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843673/
https://ncbi.nlm.nih.gov/pubmed/20178622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-60
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