Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma

BACKGROUND: Abberant DNA methylation at CpG dinucleotides represents a common mechanism of transcriptional silencing in cancer. Since CpG methylation is a reversible event, tumor supressor genes that have undergone silencing through this mechanism represent promising targets for epigenetically activ...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Rubinstein, Jill C, Tran, Nam, Ma, Shuangge, Halaban, Ruth, Krauthammer, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843643/
https://ncbi.nlm.nih.gov/pubmed/20144234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-3-4
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller