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C1q Differentially Modulates Phagocytosis and Cytokine Responses during Ingestion of Apoptotic Cells by Human Monocytes, Macrophages, and Dendritic Cells

C1q, the first component of the classical complement pathway, is also a pattern recognition receptor involved in the recognition and clearance of apoptotic cells. C1q deficiency in humans leads to development of lupus-like autoimmune disease, and it has been speculated that impaired clearance of apo...

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Autori principali: Fraser, Deborah A., Laust, Amanda K., Nelson, Edward L., Tenner, Andrea J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843563/
https://ncbi.nlm.nih.gov/pubmed/19864605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902232
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