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Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells

Genetically engineered oncolytic herpes simplex virus-1 (HSV-1) vectors selectively replicate in tumor cells causing direct killing whereas sparing normal cells. One clinical limitation of using oncolytic HSV vectors is their attenuated growth. We hypothesized that the appropriately chosen chemother...

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Detalhes bibliográficos
Main Authors: Passer, BJ, Castelo-Branco, P, Buhrman, JS, Varghese, S, Rabkin, SD, Martuza, RL
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843507/
https://ncbi.nlm.nih.gov/pubmed/19197321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.10
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